Semax
5mg · Lyophilized Powder · Purity ≥99%
Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment of adrenocorticotropic hormone, extended with a Pro-Gly-Pro sequence for stability. It is studied as a research tool in neuroprotection, neurotrophic factor regulation, and CNS signalling models.
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
Semax (MEHFPGP) does not replicate the hormonal activity of native ACTH; instead, it acts independently within the central nervous system, making it a selective research tool for neurological cell studies. Preclinical investigations have documented upregulation of BDNF expression, modulation of VEGF-A mRNA, and antioxidant activity in cell culture models. Its influence on gene expression related to immune response and vascular pathway regulation has also been a subject of in vitro inquiry. Supplied exclusively for laboratory and research use.
In cell-based research, Semax has been investigated for its capacity to upregulate brain-derived neurotrophic factor (BDNF) and modulate vascular endothelial growth factor-A (VEGF-A) mRNA levels, pointing to a role in neurotrophic signalling research. Preclinical models have examined its antioxidant properties and its effects on inflammatory pathway gene expression in the context of hypoxic neurological stress. Additional research has explored its influence on immune-related gene regulation in cerebral tissue models. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Semax |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-SEMAX5-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $30.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-SEMAX5-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Semax lyophilized powder should be stored at −20°C in a sealed, moisture-free environment to preserve peptide integrity. Repeated freeze-thaw cycles degrade the compound and should be avoided; aliquot prior to first reconstitution. Once reconstituted, store at 4°C and use within the timeframe consistent with your laboratory's standard operating procedures.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.

