Humanin
10mg · Lyophilized Powder · Purity ≥99%
Humanin is a 21-amino-acid mitochondria-derived peptide (MDP) encoded within the 16S rRNA region of the mitochondrial genome, studied for its cytoprotective and neuroprotective properties in preclinical models of cellular stress, apoptosis, and mitochondrial signalling.
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Research Overview
Humanin occupies a distinct niche in peptide research as a mitochondria-encoded signalling molecule whose receptor interactions span FPRL1/FPR2, the IL-6 receptor subunit gp130, and additional membrane-bound receptor systems. Preclinical investigations have focused on its role in apoptosis regulation, cytoprotection under oxidative and metabolic stress conditions, and signalling dynamics in ageing-related neurological cell models — where circulating and tissue Humanin levels are observed to decline with advancing age. Its characterisation as a mitochondrial-nuclear communication mediator has made it a subject of interest in both longevity biology and neuroprotection research. Supplied exclusively for laboratory and research use.
Humanin was first identified through functional cloning of a cDNA library derived from a surviving neuron population in Alzheimer's disease-affected brain tissue, marking its entry into neuroprotection and neurodegeneration research. Subsequent work has characterised its receptor engagement profile — including FPR2/FPRL1 and gp130 — and its downstream modulation of apoptotic pathways, including Bax inhibition, in preclinical cellular models. Age-dependent decline in plasma Humanin levels has positioned it as a research tool in longevity and mitochondrial function studies, where it serves as a probe for mitochondrial-nuclear signalling axes. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Humanin |
| Format | Lyophilized Powder |
| Size | 10mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-HUMANI-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $199.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-HUMANI-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Humanin lyophilized powder should be stored at −20°C in a tightly sealed vial, protected from light and moisture. Repeated freeze-thaw cycles compromise peptide integrity; aliquot prior to reconstitution to preserve material quality. Reconstituted solutions should be kept at 4°C and used within timeframes appropriate to laboratory standards.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
Research Solution Reference Calculator
Pre-filled with 10mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.

