COA Available
Sexual Wellness In Stock Research Use Only
Kisspeptin
10mg · Lyophilized Powder · Purity ≥99%
Kisspeptin is an endogenous neuropeptide encoded by the KISS1 gene, acting via the kisspeptin receptor (GPR54) to regulate GnRH pulse generation and the hypothalamic-pituitary-gonadal (HPG) axis — studied as a research tool in reproductive biology, puberty signalling, and metabolic-reproductive cross-talk.
$89.99 CAD
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Research Overview
Kisspeptin neurons within the hypothalamic arcuate nucleus (ARC) and anteroventral periventricular nucleus (AVPV) serve as the master upstream regulators of pulsatile GnRH secretion from the hypothalamus, governing downstream LH, FSH, and sex hormone release. This positioning at the apex of the HPG axis has made kisspeptin an essential research tool for studies on puberty onset mechanisms, feedback regulation by gonadal steroids, and the central integration of metabolic and reproductive signals. The KISS1/GPR54 signalling axis is also a subject of research in oncology contexts, given the KISS1 gene's originally characterised role as a metastasis suppressor in melanoma models. Supplied exclusively for laboratory and research use.
GPR54 (now designated KISS1R) is a Gq-coupled receptor whose activation by kisspeptin triggers IP3/PKC-dependent depolarisation of GnRH-secreting neurons, culminating in pulsatile GnRH release into the hypothalamic-pituitary portal circulation. Preclinical models ranging from rodent to primate have documented kisspeptin's ability to stimulate acute LH surges and sustain pulsatile LH secretion patterns — making it an indispensable probe in reproductive neuroendocrinology research. Additional research has investigated kisspeptin's role in linking nutritional status and energy balance to reproductive axis activity, particularly through interactions with leptin signalling pathways in the hypothalamus. All outcomes referenced pertain to preclinical models and do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Kisspeptin |
| Format | Lyophilized Powder |
| Size | 10mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-KISSPE-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $89.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-KISSPE-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Kisspeptin lyophilized powder should be stored at −20°C in a sealed, moisture-free vial, protected from light and temperature fluctuations. Avoid freeze-thaw cycles by preparing single-use aliquots prior to first reconstitution. Reconstituted solutions should be maintained at 4°C and used within intervals consistent with laboratory SOPs.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 10mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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