MT-1 (Melanotan I)
5mg · Lyophilized Powder · Purity ≥99%
Melanotan I (MT-1; afamelanotide) is a synthetic linear analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a selective MC1R agonist, used as a research tool in melanogenesis, pigmentation biology, and photoprotection pathway research. Supplied as a 5mg lyophilized research peptide.
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
Melanotan I is a synthetic linear peptide analogue of α-MSH that demonstrates selective agonism at the melanocortin-1 receptor (MC1R), stimulating eumelanin synthesis pathways in melanocyte cell models with reduced activity at the MC3R and MC4R subtypes compared to the closely related Melanotan II. This receptor selectivity profile makes MT-1 a useful pharmacological tool for researchers investigating MC1R-specific signalling in pigmentation biology, photoprotection-related gene expression, and melanocyte model systems. BME Health supplies Melanotan I as a lyophilized research-grade peptide at ≥98% purity. Supplied exclusively for laboratory and research use.
Preclinical and cell-based research has used Melanotan I to probe MC1R pharmacology in melanocyte models, examining downstream activation of adenylyl cyclase, cAMP elevation, and eumelanin synthesis pathway induction. Comparative studies have employed MT-1 alongside other α-MSH analogues to characterise MC1R selectivity and distinguish receptor-subtype-specific signalling outcomes. In dermatological model research, MT-1 has been investigated as a tool for studying photoprotection-related pathways in melanocyte and keratinocyte preparations. All outcomes referenced do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | MT-1 (Melanotan I) |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-MT15MG-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $49.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-MT15MG-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store lyophilized Melanotan I at −20°C in a sealed, dry container away from light. As with all α-MSH analogues, reconstituted solutions are susceptible to degradation; avoid repeated freeze-thaw cycles and prepare working solutions at the volume required for each experimental session. Vials should be inspected upon receipt and any concerns regarding packaging integrity reported to BME Health before use.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.
