COA Available
Research In Stock Research Use Only
LL-37
5mg · Lyophilized Powder · Purity ≥99%
LL-37 is a 37-amino-acid human cathelicidin antimicrobial peptide (the C-terminal fragment of hCAP18) — the only known human cathelicidin — used as a research tool in antimicrobial biology, host defence, innate immunity, and wound healing pathway research.
$109.99 CAD
Purchase Options
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
LL-37 is the sole member of the cathelicidin antimicrobial peptide family expressed in humans, generated through processing of the hCAP18 precursor protein and characterised by direct membrane-disruptive activity against both gram-positive and gram-negative bacterial targets in research models. Its capacity to bind and neutralise LPS and LTA endotoxins alongside its documented roles in immunomodulation, angiogenesis, and wound healing biology have made LL-37 a broadly employed tool in host defence peptide research. BME Health supplies LL-37 as a lyophilized high-purity research peptide at ≥98% purity with Certificate of Analysis. Supplied exclusively for laboratory and research use.
Preclinical and cell-based research has employed LL-37 to investigate direct bacterial membrane disruption mechanisms in antimicrobial biology studies, characterise LPS/LTA neutralisation kinetics, and probe innate immune receptor modulation in macrophage and epithelial cell models. Wound healing research has examined LL-37's involvement in angiogenesis signalling and keratinocyte migration models, while immunomodulation studies have explored its interactions with Toll-like receptor pathways and cytokine production profiles. Its unique status as the only human cathelicidin makes it an important reference compound for comparative host defence peptide research. All outcomes referenced do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | LL-37 |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-LL375M-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $109.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-LL375M-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store lyophilized LL-37 at −20°C in a dry environment, protected from light. LL-37 is amphipathic and prone to aggregation at certain pH and temperature ranges; reconstituted working solutions should be prepared in appropriate research-grade buffers and used promptly. Avoid repeated freeze-thaw cycles, which accelerate aggregation and reduce biological activity in research preparations.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.
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