COA Available
Research In Stock Research Use Only
Dermorphin
5mg · Lyophilized Powder · Purity ≥99%
Dermorphin is a naturally occurring heptapeptide originally isolated from South American frog skin (Phyllomedusa genus) that acts as a selective, high-affinity mu-opioid receptor (MOR) agonist, used as a pharmacological research tool in opioid receptor pharmacology and nociception signalling research.
$85.99 CAD
Purchase Options
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
Dermorphin is a heptapeptide first isolated from the skin of South American frogs of the Phyllomedusa genus and notable for containing a D-alanine residue at position 2 — an unusual structural feature for naturally occurring peptides that confers metabolic resistance and contributes to its high affinity and selectivity at the mu-opioid receptor (MOR). It has become a widely used reference compound in opioid receptor pharmacology research for MOR binding affinity characterisation, competitive displacement assays, and nociception pathway studies in preclinical models. BME Health supplies Dermorphin as a lyophilized high-purity research peptide with Certificate of Analysis. Supplied exclusively for laboratory and research use.
Preclinical research has employed Dermorphin as a pharmacological tool in MOR binding pharmacology studies, using its high selectivity and affinity to characterise mu-opioid receptor distribution, density, and signalling in CNS and peripheral tissue preparations. Nociception signalling research has used Dermorphin in animal models to probe opioid-mediated pain pathway modulation, while receptor pharmacology investigations have compared Dermorphin's MOR activity against other opioid ligands in radioligand displacement and signalling assays. Its D-amino acid content provides a useful structural comparison in studies of peptide stereochemistry and receptor selectivity. All outcomes referenced do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Dermorphin |
| Format | Lyophilized Powder |
| Size | 5mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-DERMOR-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $85.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-DERMOR-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store lyophilized Dermorphin at −20°C in a sealed, dry container protected from light. Dermorphin's D-alanine residue confers enhanced proteolytic stability compared to all-L peptides; however, reconstituted solutions should still be prepared fresh for each experimental session and repeated freeze-thaw cycles avoided to preserve ligand integrity for binding assays.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 5mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.
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