COA Available
GLP-1 In Stock Research Use Only
Mazdutide
10mg · Lyophilized Powder · Purity ≥99%
Mazdutide (IBI362/LY3305677) is a synthetic dual agonist of the GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR), used as a research tool to probe dual-incretin pathway activation and hepatic lipid metabolism in preclinical metabolic models.
$169.99 CAD
Purchase Options
Subscriptions can be managed from your customer account. Prices in CAD.
Research Overview
Mazdutide is a synthetic once-weekly peptide that co-activates both the GLP-1 receptor (GLP-1R) and the glucagon receptor (GCGR), providing a pharmacological research tool for investigating the combined effects of incretin signalling — including insulin secretion modulation and appetite-suppressive pathways — alongside GCGR-mediated energy expenditure mechanisms operating through cAMP/PKA signalling in hepatocyte and brown adipose tissue models. The compound has been used in metabolic research examining dual-receptor pathway biology and hepatic lipid handling. BME Health supplies Mazdutide as a lyophilized high-purity research peptide with Certificate of Analysis. Supplied exclusively for laboratory and research use.
Preclinical and clinical pharmacology research has used mazdutide to examine the mechanistic interplay between GLP-1R and GCGR co-activation in metabolic tissue models, with investigations reporting changes in markers of hepatic lipid accumulation, energy expenditure, and glucose homeostasis in preclinical settings. Phase 3 data from the GLORY-1 trial were published in the New England Journal of Medicine (2025), and the compound has received NMPA approval in China; it is not approved by Health Canada or the FDA. All BME Health supply is strictly for research use. All outcomes referenced do not constitute evidence of clinical efficacy or safety in humans.
Specifications
| Compound | Mazdutide |
| Format | Lyophilized Powder |
| Size | 10mg |
| Purity (HPLC) | ≥99% |
| Item # | BME-MAZDUT-A |
| Storage | −20°C, dry, dark |
| Price (CAD) | $169.99 |
COA / Testing
Batch documentation and third-party testing information are available for batch BME-MAZDUT-A. COA previews appear only when documentation exists for the active batch.
Storage & Handling
Store lyophilized Mazdutide at −20°C in a sealed, dry container protected from light. Avoid repeated freeze-thaw cycles after reconstitution; prepare working solutions in appropriate research-grade buffered vehicles as required for each experimental run. Vials should be inspected for integrity upon receipt.
Shipping & Returns
Orders are processed on business days. Packaging is selected to maintain compound integrity in transit. Shipping timelines and return conditions are outlined in full in the Shipping & Returns policy — review before checkout if you have specific requirements. For orders with time-sensitive research schedules, contact support before placing your order.
Research Use Disclaimer
This product is supplied strictly for in-vitro and laboratory research use. It is not a drug, food supplement, or cosmetic and is not approved for human or veterinary clinical applications, diagnostics, or therapeutic use. Researchers are responsible for compliance with all applicable institutional and regulatory requirements in their jurisdiction.
Preparation Reference Guide
Research Solution Reference Calculator
Pre-filled with 10mg. Enter your solvent volume and target amount to see concentration and units on a U-100 syringe scale.
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For research-use calculations only. Always verify measurements independently — not medical guidance.
Questions before you order?
Browse the FAQ for documentation, storage, and sourcing answers, or contact our support team directly. We aim to respond to all research procurement inquiries within one business day.
